Endocrine Abstracts

Erythrocytosis is classified as either primary or secondary. Polycythemia vera (PV), a myeloproliferative neoplasm, is often caused by a mutation in exon 12 of the Janus kinase 2 (JAK2) tyrosine kinase gene which phosphorylates erythropoietin receptor (EPO-R) at multiple sites. Secondary erythrocytosis mainly results in conditions with increased erythropoietin (EPO) production. We report a 21-year-old man with metastatic medullary thyroid carcinoma (MTC) at diagnosis. The tota...